Found 33 matching trials
Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia PHASE1 This phase I trial studies the side effects and the best dose of trebananib...
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Roswell Park Cancer Institute
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Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients PHASE2 This is a phase 2, randomized, placebo controlled, multi-center study to es...
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AMG 386 Drug-Drug Interaction Study With Paclitaxel PHASE1 The purpose of this study is to evaluate the pharmacokinetics of paclitaxel...
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University of Colorado Cancer Center
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A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma PHASE2 This clinical trial will compare the efficacy and safety of the combination...
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Multiple Locations
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Study Evaluating AMG 386 in Adult Patients With Advanced Solid Tumors PHASE1 The purpose of this study is to test the safety, tolerability and pharmacok...
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Multiple Locations
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Amgen 386 for Recurrent Glioblastoma PHASE1 Primary Objectives
Cohort A -- monotherapy:
To determine the efficacy of ...
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University of California Los Angeles
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Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer PHASE1 To evaluate whether AMG 386 in combination with paclitaxel and carboplatin ...
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To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib. PHASE1 The purpose of this study is to evaluate the safety, tolerability and pharm...
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Multiple Locations
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AMG 386 Phase 2 Open-Label Renal Cell Carcinoma (RCC) Study 1st Line or After Cytokine Failure in Combination With Sunitinib PHASE2 This phase 2 study is an open-label, multi-center study to determine the sa...
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Multiple Locations
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Dual Targeting of Vascular Endothelial Growth Factor-A Together With Angiopoietins in Chemotherapy-naïve Metastatic Colorectal Cancer PHASE2 This is a clinical trial investigating the effectiveness and safety of the ...
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